Type 2 diabetes diminution said to be possible with weight loss


It is said people who achieve a weight loss of 10% or more in the first five years following diagnosis with type 2 diabetes have the utmost chance of seeing their disease go into diminution, suggested by a study led by the University of Cambridge. The findings suggest that it is possible to recover from the disease without intensive lifestyle interventions or extreme calorie restrictions.


Type 2 diabetes affects 400 million people worldwide and increases the risk of heart disease, stroke, blindness, and amputations. While the disease can be managed through a combination of positive lifestyle changes and medication, it is also possible for the high blood glucose levels that define diabetes to return to normal—through significant calorie restriction and loss. An intensive low-calorie diet involving a total daily intake of 700 calories (less than one cheeseburger) for 8 weeks has been associated with remission in almost nine out of ten people with recently diagnosed diabetes and in half of the people with longstanding disease.


However, there is little evidence to show whether the same effect can be achieved by people undergoing less intensive interventions, which are more feasible and potentially scalable to the wider population. To answer this question, a team led by researchers at the University of Cambridge studied data from the ADDITION-Cambridge trial, a prospective cohort study of 867 people with newly diagnosed diabetes aged 40 and 69 years recruited from general practices in the eastern region.


“We’ve known for some time now that it’s possible to send diabetes into remission using fairly drastic measures such as intensive weight loss programs and extreme calorie restriction”, says Dr.Hajira Dambha-Miller from the Department of Public Health and Primary Care. However, it has been reported, in order to clarify the best way to help patients with type 2 diabetes achieve sustained weight loss, the team is currently undertaking a study called GLoW ( Glucose lowering through weight management).


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